Background：Regulator of G protein signaling （RGS） family members are regulatory molecules that act as GTPase activating proteins （GAPs） for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Regulator of G protein signaling 10,Regulator of G-protein signaling 10,RGS10,RGS10
Host：Rabbit
Reactivity：Human,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human RGS10
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
