Background：Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components： P protein （a pyridoxal phosphate-dependent glycine decarboxylase）, H protein （a lipoic acid-containing protein）, T protein （a tetrahydrofolate-requiring enzyme）, and L protein （a lipoamide dehydrogenase）. The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia （NKH）.
仕様
Synonyms：GCE,GCSP,GCSP,GLDC,Glycine cleavage system P protein,glycine cleavage system protein P,Glycine decarboxylase,glycine decarboxylase P protein ,Glycine dehydrogenase （decarboxylating） mitochondrial,Glycine dehydrogenase [decarboxylating], mitochondrial,Gycine dehydrogenase （decarboxylating）,HYGN1,MGC138198,MGC138200,NKH
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human GLDC
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：200 - 1：500
Gene_ID（human）：2731
Swissprot：P23378
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
