Background：This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia.
仕様
Synonyms：ANK,ANKH,ANKH,Ankylosis progressive homolog （mouse）,Ankylosis progressive homolog,CCAL 2,CCAL2,CMDJ,CPPDD,Craniometaphyseal dysplasia Jackson type （dominant）,FLJ27166,HANK,MANK,Progressive ankylosis protein homolog
Host：Rabbit
Reactivity：Human
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human ANKH
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
