Background:This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
仕様
Synonyms:C-type lectin domain family 13 member E,C-type mannose receptor 2,CD 280,CD280,CD280 antigen,CLEC 13E,CLEC13E,ENDO 180,ENDO180,Endocytic receptor (macrophage mannose receptor family),Endocytic receptor 180,FLJ35911,KIAA0709,Macrophage mannose receptor 2,Mannose receptor C type 2,MRC 2,MRC2,MRC2,UPAR-associated protein,UPARAP,Urokinase plasminogen activator receptor associated protein,Urokinase receptor associated protein,Urokinase receptor-associated protein,Urokinase-type plasminogen activator receptor-associated protein
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human MRC2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.