Background：This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Dynamin like 120 kDa protein,Dynamin like 120 kDa protein, mitochondrial,Dynamin-like 120 kDa protein, form S1,FLJ12460,Juvenile kjer type optic atrophy,KIAA0567,KJER type,Large GTP binding protein,largeG,MGM1,Mitochondrial dynamin like 120 kDa protein,Mitochondrial dynamin like GTPase,NPG,NTG,OAK,OPA 1,opa1,OPA1 gene,OPA1,Optic atrophy 1 （autosomal dominant）,OPTIC ATROPHY 1,Optic atrophy 1 gene protein,Optic atrophy 1 homolog （human）,Optic atrophy protein 1,Optic atrophy protein 1 homolog
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human OPA1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：4976
Swissprot：O60313
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Neuroscience
