Background：This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 （GS1）, Griscelli syndrome type-3 （GS3） and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
仕様
Synonyms： non-muscle,Dilute myosin heavy chain,GS1,MYH12,MYO5,Myo5a,MYO5A,Myosin heavy chain 12,Myosin heavy polypeptide kinase,Myosin V,Myosin VA （heavy polypeptide 12 myoxin） ,Myosin VA （heavy polypeptide 12 myoxin）,Myosin-12,Myoxin,MYR12,Unconventional myosin-Va
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human MYO5A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：4644
Swissprot：Q9Y4I1
Isotype：IgG
Research Areas：Metabolism, Neuroscience, Signal transduction
