Background：This gene encodes a Jumonji- and AT-rich interaction domain （ARID）-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 （PRC2） which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.
仕様
Synonyms：JARD2,JARD2,JARID2,JMJ,Jumonji AT rich interactive domain 2 ,Jumonji homolog,Jumonji like protein,Jumonji protein,Jumonji/ARID domain containing protein 2,Jumonji/ARID domain-containing protein 2,Protein Jumonji
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human JARID2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：3720
Swissprot：Q92833
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Neuroscience
