Background：This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
仕様
Synonyms：Cadherin family member 4,CDHF4,Desmoglein-1,Desmosomal glycoprotein 1,DG1,DGI,DSG,DSG1,DSG1,EPKHE,EPKHIA,Pemphigus foliaceus antigen,PPKS1,SPPK1
Host：Rabbit
Reactivity：Human,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human DSG1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
