Background:This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.
仕様
Synonyms:CO4A5,COL4A5,Collagen alpha-5(IV) chain
Host:Rabbit
Reactivity:Human
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human COL4A5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):1287
Swissprot:P29400
Isotype:IgG
Research Areas:Cancer, Signal transduction, Stem cells