Background：This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
仕様
Synonyms：hSCOP,KIAA0606,PH domain and leucine rich repeat protein phosphatase,PH domain leucine rich repeat containing protein phosphatase,PH domain leucine rich repeat protein phosphatase,PH domain leucine-rich repeat-containing protein phosphatase 1,PH domain-containing family E member 1,PHLP1,PHLPP,Phlpp1,Pleckstrin homology domain containing family E （with leucine rich repeats） member 1,Pleckstrin homology domain containing family E protein 1,Pleckstrin homology domain-containing family E member 1,PLEKHE 1 protein,PLEKHE1,SCN circadian oscillatory protein,SCOP,Suprachiasmatic nucleus circadian oscillatory protein,Suprachiasmatic nucleus circadian protein
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human PHLPP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
