Background：This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
仕様
Synonyms：ARVC 10,ARVC10,ARVD 10,ARVD10,Cadherin family member 5,CDHF 5,CDHF5,CMD1BB,Desmoglein 2,Desmoglein-2,Desmoglein2,DSG 2,DSG2,DSG2,HDGC,HDGC included,Human Desmoglein colon,MGC117034,MGC117036,MGC117037
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human DSG2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：1829
Swissprot：Q14126
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Signal transduction
