Background:The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.
仕様
Synonyms:Alpha 1,6 mannosyl glycoprotein 2 beta N acetylglucosaminyltransferase,Beta 1,2 N acetylglucosaminyltransferase II,CDG2A,CDGS2,GlcNAc T II ,GLCNACTII,GNT II,GNT2,Mannoside acetylglucosaminyltransferase 2,N glycosyl oligosaccharide glycoprotein N acetylglucosaminyltransferase II,UDP N acetylglucosamine:alpha 6 D mannoside beta 1,2 N acetylglucosaminyltransferase II
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human MGAT2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.