Background:The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.
仕様
Synonyms:2510048O06Rik,C13orf12,Chromosome 13 open reading frame 12 ,HSPC 014,HSPC036 protein ,hUMP 1,hUMP1,PNAS 110,PNAS110,Pomp,POMP,Proteasome maturation protein,Proteassemblin,Protein UMP1 homolog,UMP 1,UMP1,UMP1, yeast, homolog of,Voltage gated K channel beta subunit 4.1 ,Voltage-gated K channel beta subunit 4.1,voltage-gated potassium channel beta subunit 4.1
Host:Rabbit
Reactivity:Human
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human POMP
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:1000
Gene_ID(human):51371
Swissprot:Q9Y244
Isotype:IgG
Research Areas:Cancer, Cell Biology, Signal transduction