Background:Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.
仕様
Synonyms:Vesicle Associated Membrane Protein 1,VAMP-1,SYB1,Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1),Vesicle-Associated Membrane Protein 1,Synaptobrevin 1,Synaptobrevin-1,SPAX1.
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human VAMP1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:2000
Gene_ID(human):6843
Swissprot:P23763
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction