Background:Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13.
仕様
Synonyms:Farnesyltransferase, CAAX Box, Alpha,Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha,Protein Prenyltransferase Alpha Subunit Repeat Containing 2,Ras Proteins Prenyltransferase Subunit Alpha,GGTase-I-Alpha,FTase-Alpha,Type I Protein Geranyl-Geranyltransferase Alpha Subunit,Type I Protein Geranyl-Geranyltransferase Subunit Alpha.
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human FNTA
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):2339
Swissprot:P49354
Isotype:IgG
Research Areas:Cancer, Cell Biology, Signal transduction