Background：Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：Dual specificity phosphatase 10,Dual specificity phosphatase MKP 5,Dual specificity phosphatase MKP5,Dual specificity protein phosphatase 10,DUS10,DUSP 10,DUSP10,DUSP10 protein,MAP kinase phosphatase 5,Mitogen activated protein kinase phosphatase 5,Mitogen-activated protein kinase phosphatase 5,MKP 5,MKP-5,MKP5,Serine/threonine specific protein phosphatase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human DUSP10
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
