Background：The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.
仕様
Synonyms：26g turgor protein homolog,AL7A1,Aldehyde dehydrogenase 7 A1,Aldehyde dehydrogenase 7 family, member A1,Aldehyde dehydrogenase family 7 member A1,ALDH7A1,Alpha AASA dehydrogenase,Alpha aminoadipic semialdehyde dehydrogenase,Alpha-AASA dehydrogenase,Alpha-aminoadipic semialdehyde dehydrogenase,Antiquitin 1,Antiquitin,Antiquitin-1,ATQ1,Betaine aldehyde dehydrogenase,Delta1 piperideine 6 carboxylate dehydrogenease,Delta1-piperideine-6-carboxylate dehydrogenase,EPD,P6c dehydrogenase,PDE
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ALDH7A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：1000 - 1：4000
Gene_ID（human）：501
Swissprot：P49419
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
