Background:This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
仕様
Synonyms:DAPK-interacting protein 1,Dip 1,DIP-1,Dip1,E3 ubiquitin protein ligase MIB 1,E3 ubiquitin protein ligase MIB1,E3 ubiquitin-protein ligase mib1,KIAA1323,LVNC7,MIB,mib1,MIB1,Mind bomb homolog 1,Mindbomb E3 ubiquitin protein ligase 1,Ubiquitin ligase mind bomb,Zinc finger ZZ type with ankyrin repeat domain protein 2,ZZANK2,ZZZ6
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human MIB1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.