Background：This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element （MTE） of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may （1） play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, （2） act as a transcriptional activator of the heme-oxygenase-1 gene, and （3） be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：GATA 3 binding protein G3B,GATA-3-binding protein G3B,HUMHOXY1,Lysine N methyltransferase 8,Lysine N-methyltransferase 8,MTB ZF,MTB-ZF,MTE binding protein,MTE-binding protein,PR domain containing 2 with ZNF domain,PR domain containing protein 2,PR domain zinc finger protein 2,PR domain-containing protein 2,PRDM2,PRDM2,Retinoblastoma protein binding zinc finger protein,Retinoblastoma protein interacting zinc- inger protein,Retinoblastoma protein-interacting zinc finger protein,RIZ,RIZ-LSB,RIZ1,RIZ2,Zinc finger DNA binding protein,Zinc finger protein RIZ
Host：Rabbit
Reactivity：Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human PRDM2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：7799
Swissprot：Q13029
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Neuroscience
