Background：The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：AI852829,AMKL,AW743281,AW821984,Basic SAP coiled-coil transcription activator,Bsac,KIAA1438,Mal,Megakaryoblastic leukemia 1 protein,Megakaryocytic acute leukemia protein,MKL （megakaryoblastic leukemia）/myocardin like 1,MKL/myocardin like protein 1,MKL/myocardin-like protein 1,Mkl1,MKL1,MRTF A,Mrtf A,MRTF-A,MRTFA,MYOCARDIN RELATED PROTEIN,Myocardin related transcription factor A,Myocardin-related transcription factor A
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human MKL1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：57591
Swissprot：Q969V6
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction, Stem cells
