Background:This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms:68 kDa TATA-binding protein-associated factor,Npl3,RBP56,RBP56,RNA binding protein 56,RNA-binding protein 56,TAF,TAF(II)68,TAF15,TAF15 RNA polymerase II TATA box binding protein (TBP) associated factor 68kDa,TAF2N,TAFII68,TATA-binding protein-associated factor 2N
Host:Rabbit
Reactivity:Human
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human TAF15
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:100
Gene_ID(human):8148
Swissprot:Q92804
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling