Background:Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.
仕様
Synonyms:MGC32628,OCT 2,OCT2,Organic cation transporter 2,Organic cation transporter,RP11-317M22.2,Solute carrier family 22 (organic cation transporter) member 2,Solute carrier family 22 member 2
Host:Rabbit
Reactivity:Human,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human SLC22A2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):6582
Swissprot:O15244
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction