Background:This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:hPCl1,MTF2 L2,MTF2L 2,MTF2L2,PCL 1,PCL1,PHD finger protein 1,PHD finger protein1,PHF 1,PHF 2,Phf1,PHF1,PHF2,Plc 1,Plc1,Polycomb like protein 1,Polycomb like protein1,Polycomb-like protein 1,Protein PHF1,T complex testis expressed 3,T complex testis expressed3,Tctex 3,Tctex3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human PHF1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):5252
Swissprot:O43189
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling