Background:HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
仕様
Synonyms:HLA class I histocompatibility antigen E alpha chain,EA1.2,EA2.1,HLA 6.2,HLA class I histocompatibility antigen alpha chain E,HLA class I histocompatibility antigen E alpha chain precursor ,HLA class I histocompatibility antigen E alpha chain precursor,HLA6.2,HLAE,Lymphocyte antigen,Major histocompatibility complex class I E,MHC,MHC class I antigen E,MHC HLA E alpha 1,MHC HLA E alpha 2.1,QA1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human HLA-E
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.