Background:This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.
仕様
Synonyms:130 kD pemphigus vulgaris antigen,130 kDa pemphigus vulgaris antigen,Balding,Cadherin family member 6,CDHF 6,CDHF6,Desmoglein 3,Desmoglein 3 precursor ,Desmoglein-3,Desmoglein3,DKFZp686P23184,DSG 3,DSG3,DSG3,Pemphigus vulgaris antigen,PVA
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human DSG3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.