Background:This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene.
仕様
Synonyms:Corticotropin releasing factor type 1 receptor,corticotropin releasing hormone receptor 1,Corticotropin-releasing factor receptor 1,Corticotropin-releasing hormone receptor 1,CRF R,crf receptor 1,crf receptor type 1,crf type 1,CRF-R,CRF-R-1,CRF-R1,CRF1,CRFR,CRFR-1,CRFR1,CRFR1,CRH-R-1,CRH-R1,CRH-R1h,CRHR,Crhr1,CRHR1f,CRHR1L
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human CRHR1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):1394
Swissprot:P34998
Isotype:IgG
Research Areas:Cancer, Metabolism, Neuroscience, Signal transduction