Background:Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.
仕様
Synonyms:COX7A2,COX7AL,COX7AL1,COXVIIa L,COXVIIAL,CX7A2,Cytochrome c oxidase polypeptide 7A2 mitochondrial,Cytochrome c oxidase polypeptide VIIa liver/heart,Cytochrome c oxidase subunit 7A2,Cytochrome c oxidase subunit 7A2 mitochondrial,Cytochrome c oxidase subunit VIIa polypeptide 2,Cytochrome c oxidase subunit VIIa-L,Cytochrome c oxidase subunit VIIa-liver/heart,Cytochrome c oxidase subunit VIIaL,Hepatic cytochrome c oxidase chain VIIa,MGC118950,MGC118951,MGC118952,MGC126875,MGC126877,mitochondrial,VIIAL
Host:Rabbit
Reactivity:Human
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human COX7A2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.