Background:This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development.
仕様
Synonyms:CRISTIN1,hPWTSR,hRspo3,Protein with TSP type-1 repeat,PWTSR,R-spondin 3 homolog,R-spondin-3 [Precursor],R-spondin-3,Roof plate specific spondin-3,Roof plate-specific spondin-3,RSPO3,RSPO3,Thrombospondin type I domain containing 2,Thrombospondin type-1 domain-containing protein 2,THSD2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human RSPO3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.