Background：This gene encodes a component of the nucleotide excision repair （NER） pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum （XP） A-G and V, Cockayne syndrome （CS） A and B, and trichothiodystrophy （TTD） group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
仕様
Synonyms：DNA repair protein complementing XP C cells,DNA repair protein complementing XP-C cells,DNA repair protein complementing XPC cells ,p125,RAD4,Xeroderma pigmentosum complementation group C,Xeroderma pigmentosum group C complementing protein,Xeroderma pigmentosum group C protein,Xeroderma pigmentosum group C-complementing protein,Xeroderma pigmentosum group III,XP 3,XP C,XP group C,XP3,Xpc,XPC gene,XPC,XPCC
Host：Rabbit
Reactivity：Human
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human XPC
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
