Background:The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
仕様
Synonyms:E3 ubiquitin protein ligase RNF5,E3 ubiquitin-protein ligase RNF5,G16,HsRma1,NG2,OTTHUMP00000029107,Protein G16,Ram1 homolog,RING finger protein 5,RING5,RMA1,RNF 5,RNF5,RNF5
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human RNF5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):6048
Swissprot:Q99942
Isotype:IgG
Research Areas:Cancer, Cell Biology, Immunology, Microbiology