Background：The protein encoded by this gene is a member of the tripartite motif （TRIM） family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
仕様
Synonyms：ADP ribosylation factor domain protein 1,ADP-ribosylation factor domain-containing protein 1,ARF domain protein 1,ARFD1,E3 ubiquitin-protein ligase TRIM23,GTP binding protein ARD 1,GTP-binding protein ARD-1,N-acetyltransferase ARD1 human homolog of,N-acetyltransferase homolog of S. cerevisiae ARD1,RING finger protein 46,TRI23,TRIM23,Tripartite motif protein TRIM23,Tripartite motif-containing protein 23
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human TRIM23
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
