Background：This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.
仕様
Synonyms：BAR,Bile acid receptor,Farnesoid X activated receptor,Farnesoid X receptor,Farnesoid X-activated receptor,Farnesol receptor HRR 1,Farnesol receptor HRR-1,Farnesol receptor HRR1,FXR,HRR 1,HRR1,NR1H4,NR1H4,Nuclear receptor subfamily 1 group H member 4,Retinoid X receptor interacting protein 14,Retinoid X receptor-interacting protein 14,RIP 14,RIP14,RXR interacting protein 14 ,RXR-interacting protein 14
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human NR1H4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：9971
Swissprot：Q96RI1
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Metabolism, Signal transduction
