Background：Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes （mitoribosomes） consist of a small 28S subunit and a large 39S subunit. They have an estimated 75％ protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex.
仕様
Synonyms：39S ribosomal protein L12,39S ribosomal protein L12,mitochondrial,5c5-2,FLJ60124,L12mt,MGC8610,mitochondrial,Mitochondrial ribosomal protein L12,MRP-L12,MRP-L31/34,MRPL12,MRPL7,MRPL7/L12,RM12,RPML12
Host：Rabbit
Reactivity：Human
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human MRPL12
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：100
Gene_ID（human）：6182
Swissprot：P52815
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Metabolism
