Background:This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
仕様
Synonyms:3 oxoacid CoA transferase 1,3-oxoacid CoA-transferase 1,EC 2.8.3.5,OTTHUMP00000120012,OTTHUMP00000221550,OXCT,Oxct1,SCOT,Scot S,Scot-S,SCOT1,Somatic type succinyl CoA:3 oxoacid CoA transferase,Somatic-type succinyl-CoA:3-oxoacid CoA-transferase,Succinyl CoA:3 ketoacid CoA transferase,Succinyl CoA:3 ketoacid coenzyme A transferase 1 mitochondrial,Succinyl CoA:3 oxoacid CoA transferase,Succinyl-CoA:3-ketoacid coenzyme A transferase 1,mitochondrial
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human OXCT1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:100
Gene_ID(human):5019
Swissprot:P55809
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction