Background:The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).
仕様
Synonyms:DNA excision repair protein ERCC 4,DNA excision repair protein ERCC-4,DNA excision repair protein ERCC4,DNA repair endonuclease XPF,DNA repair protein complementing XP F cells,DNA repair protein complementing XP-F cells,ERCC 11,ERCC 4,ERCC11,ERCC4,Excision repair complementing defective in Chinese hamster,Excision repair cross complementing rodent repair deficiency complementation group 4,excision repair cross-complementation group 4,FANCQ,RAD 1,RAD1,Xeroderma pigmentosum complementation group F,Xeroderma pigmentosum group F complementing protein,Xeroderma pigmentosum group F-complementing protein,Xeroderma pigmentosum VI,XP,group G,XP6,XPF
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IP
Concentration:1mg/ml
Immunogen:Recombinant protein of human ERCC4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IP1:20 - 1:50
Gene_ID(human):2072
Swissprot:Q92889
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling