Background:The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms:HGL,Human giant larvae homolog,L2GL2,L2GL2,Lethal 2 giant larvae protein homolog 2,Lethal giant larvae homolog 2,Lethal(2) giant larvae protein homolog 2,LGL2,LLGL2
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:A synthetic peptide of mouse LLGL2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.