Background：The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
仕様
Synonyms：ACOX,ACOX1,ACOX1,Acyl CoA oxidase 1 palmitoyl,Acyl CoA oxidase straight chain,AOX,EC 1.3.3.6,PALMCOX,Palmitoyl CoA oxidase,Palmitoyl-CoA oxidase,Peroxisomal acyl coenzyme A oxidase 1,Peroxisomal acyl-coenzyme A oxidase 1,Peroxisomal fatty acyl CoA oxidase,SCOX,Straight chain acyl CoA oxidase,Straight-chain acyl-CoA oxidase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human ACOX1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000 IHC 1：100 - 1：200
Gene_ID（human）：51
Swissprot：Q15067
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
