Background:This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.
仕様
Synonyms:11 cis RDH,11 cis retinol dehydrogenase,9 cis retinol specific dehydrogenase,FLJ39337,FLJ97089,HSD17B9,RDH 5,RDH1,Retinol dehydrogenase 1,Retinol dehydrogenase 5 (11 cis/9 cis),Retinol dehydrogenase 5,SDR9C5,Short chain dehydrogenase/reductase family 9C member 5
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human RDH5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.