Background：The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：3 hydroxy 3 methylglutaryl CoA lyase,3 hydroxy 3 methylglutaryl Coenzyme A lyase,3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase （hydroxymethylglutaricaciduria）,3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase,3-hydroxy-3-methylglutarate-CoA lyase,HL,HMG CoA lyase,HMG CoA Lyase Deficiency,HMG-CoA lyase,HMGCL,HMGCL,Hydroxymethylglutaricaciduria,Hydroxymethylglutaryl CoA lyase,Hydroxymethylglutaryl CoA lyase mitochondrial,Hydroxymethylglutaryl-CoA lyase,Mitochondrial 3 hydroxy 3 methylglutaryl CoA lyase,mitochondrial,MS725,OTTHUMP00000044830
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human HMGCL
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：3155
Swissprot：P35914
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
