Background：This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine （TARC） and macrophage inflammatory protein-1 beta （MIP-1 beta） have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
仕様
Synonyms：C C chemokine receptor type 8,C C CKR 8,C C motif chemokine receptor 8,C-C chemokine receptor type 8,C-C CKR-8,CC chemokine receptor 8,CC chemokine receptor CHEMR1,CC chemokine receptor type 8,CC CKR 8,CC-CKR-8,CCR 8,CCR-8,Ccr8,CCR8 protein,CCR8-L,CCR8,CDw198,CDw198 antigen,Chemokine （C C motif） receptor 8,Chemokine （C C） receptor 8,Chemokine （C C） receptor like 2,Chemokine （CC motif） receptor 8,Chemokine （CC） receptor 8,Chemokine （CC） receptor like 1,Chemokine （CC） receptor like 2,Chemokine C C motif receptor 8,Chemokine C C receptor 8,Chemokine CC motif receptor 8,Chemokine CC receptor 8,Chemokine receptor 8,Chemokine receptor like 1,Chemokine receptor-like 1,CKR L1,CKR-L1,CKRL 1,CKRL1,CMKBR 8,CMKBR L2,CMKBR8,CMKBRL 2,CMKBRL2,CY 6,CY6,GPR CY6,GPR-CY6,GPRCY6,MGC123958,MGC123959,MGC129966,MGC129973,TER 1,TER1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human CCR8
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
