Background：The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
仕様
Synonyms：Kinase responsive to stress,Krs2,Mammalian STE20 like protein kinase 1,Mammalian STE20-like protein kinase 1,Mammalian sterile 20 like 1,MST-1,MST1,Serine/threonine kinase 4,Serine/threonine protein kinase Krs 2,Serine/threonine-protein kinase 4,Serine/threonine-protein kinase Krs-2,STE20 like kinase MST1,STE20-like kinase MST1,STK4,STK4,TIIAC,YSK3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,IP
Concentration：1mg/ml
Immunogen：Recombinant protein of human STK4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
