Background:This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:DKFZp781H0695,HSPC137,MGC8900,Rab 23,RAB family small GTP binding protein RAB 23,Rab23,RAB23, member RAS oncogene family,RAB23,Ras related protein Rab 23,Ras-related protein Rab-23
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human RAB23
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):51715
Swissprot:Q9ULC3
Isotype:IgG
Research Areas:Neuroscience, Signal transduction, Stem cells