Background:This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
仕様
Synonyms:Dendritic derived BTB/POZ zinc finger protein ,Dendritic-derived BTB/POZ zinc finger protein,DKFZp566F123,DPZF,HOF,ODA 8S,OTTHUMP00000215066 ,OTTHUMP00000215067,OTTHUMP00000215069,OTTHUMP00000215071 ,ZBT20,Zbtb20,zinc finger 288,zinc finger and BTB domain containing 20 ,Zinc finger and BTB domain-containing protein 20,Zinc finger protein 288,ZNF288
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human ZBTB20
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):26137
Swissprot:Q9HC78
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling