Background:This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex.
仕様
Synonyms:DIRA3,DIRA3,DIRAS family GTP binding RAS like 3,DIRAS family GTPase 3,DIRAS family,GTP-binding RAS-like protein 3,DIRAS3,Distinct subgroup of the Ras family member 3,GTP binding protein Di Ras3,GTP-binding protein Di-Ras3,NOEY2,Ras homolog gene family member I,Rho related GTP binding protein RhoI,Rho-related GTP-binding protein RhoI,RHOI
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human DIRAS3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.