Background:This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form.
仕様
Synonyms:A disintegrin and metalloproteinase domain 12,ADA12,ADAM 12,ADAM metallopeptidase domain 12,ADAM12,CAR10,Disintegrin and metalloproteinase domain-containing protein 12,MCMP,MCMPMltna,Meltrin alpha,Meltrin-alpha,Metalloprotease disintegrin 12 transmembrane,MLTN,MLTNA,OTTHUMP00000046766
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human ADAM12
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:100 - 1:200
Gene_ID(human):8038
Swissprot:O43184
Isotype:IgG
Research Areas:Cancer, Cell Biology, Signal transduction