Background:This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:1200015H23Rik,6 phosphofructokinase type C,6 phosphofructokinase,platelet type,6-phosphofructokinase,6-phosphofructokinase type C,9330125N24Rik,FLJ40226,K6PP,K6PP,MGC105718,PFK C,PFK,fibroblast type,PFK-C,PFKF,PFKP,Phosphofructo 1 kinase isozyme C,Phosphofructo-1-kinase isozyme C,Phosphofructokinase 1,Phosphofructokinase platelet,Phosphohexokinase,platelet type
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human PFKP
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:100 - 1:200
Gene_ID(human):5214
Swissprot:Q01813
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction