Background：The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Aes 1,Aes 2,aes,AES,Aes1,Aes2,Amino enhancer of split,Amino terminal enhancer of split,Amino-terminal enhancer of split,Esp 1,Esp1,Gp130 associated protein GAM,Gp130-associated protein GAM,GRG 5,GRG,GRG protein,Grg-5,GRG5,Groucho-related protein 5,Protein ESP 1,Protein ESP1,Protein GRG,TLE 5,TLE5
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human AES
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：100
Gene_ID（human）：166
Swissprot：Q08117
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Stem cells
