Background:The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms:ACAD 6,ACAD6,ACADV,Acadvl,Acyl CoA dehydrogenase very long chain,Acyl Coenzyme A dehydrogenase very long chain,LCACD,mitochondrial,Very long chain specific acyl CoA dehydrogenase,Very long chain specific acyl CoA dehydrogenase mitochondrial,Very long-chain specific acyl-CoA dehydrogenase,VLCAD
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human ACADVL
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:2000
Gene_ID(human):37
Swissprot:P49748
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction