Background：Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 （Atg4） family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：9830134P12Rik,APG4 autophagy 4 homolog D,APG4 D,APG4,S. cerevisiae,homolog of,D,APG4D,ATG4 autophagy related 4 homolog D （S. cerevisiae）,Atg4d,ATG4D,Atg4dl,AUT like 4 cysteine endopeptidase,AUT-like 4 cysteine endopeptidase,AUTL4,Autophagin 4,Autophagin-4,autophagy 4,S. cerevisiae,homolog of,D,autophagy related 4D,cysteine peptidase,Autophagy related cysteine endopeptidase 4,Autophagy related protein 4 homolog D,Autophagy-related cysteine endopeptidase 4,Autophagy-related protein 4 homolog D,Cysteine protease ATG4D,Cysteine protease involved in autophagy,MGC31226
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ATG4D
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000
Gene_ID（human）：84971
Swissprot：Q86TL0
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction
