Background:This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.
仕様
Synonyms:AIDA,AIDA-1,Amyloid-beta protein intracellular domain-associated protein 1,Anks1b,ANKS2,Ankyrin repeat and sterile alpha motif domain containing 1B,Ankyrin repeat and sterile alpha motif domain-containing protein 1B,ANS1B,Cajalin 2,E2A-PBX1-associated protein,EB-1,EB1,MGC26087
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human ANKS1B
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.